Tue 04/Aug/2009

   Tue 04/Aug/2009

   Epigenetic code

   Epigenetic code is a defining code in every eukaryotic cell consisting of the specific epigenetic modification in each cell. Histone modifications defined by the histone code and additional epigenetic modifications such as DNA methylation are a part of the epigenetic code. Acetylation of the N-terminal tail domains of core histones is a well known source of epigenetic information that operate as part of a predictive and heritable epigenetic code that specifies patterns of gene expression through differentiation and development. Moreover the base for the epigenetic code is a system above the genetic code of a single cell. The genetic code in each cell of an individual is the same, but the epigenetic code is tissue and cell specific. The epigenetic code may be read (ie. exert a functional effect) either through non-histone proteins that bind in an acetylation-dependent manner, or through direct effects on chromatin structure. Imgenex Corp., USA is supplying antibodies which can explore the epigenetic code more elaborately.
http://www.imgenex.com/